Detalhe da pesquisa
1.
Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity.
Pharmacol Rev
; 75(3): 463-486, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36627212
2.
Statins affect human iPSC-derived cardiomyocytes by interfering with mitochondrial function and intracellular acidification.
Basic Res Cardiol
; 119(2): 309-327, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38305903
3.
Impact of tyrosine kinase inhibitors on glucose control and insulin regulation in patients with chronic myeloid leukemia.
Am J Physiol Endocrinol Metab
; 324(3): E209-E216, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36696600
4.
Ndufs4 knockout mouse models of Leigh syndrome: pathophysiology and intervention.
Brain
; 145(1): 45-63, 2022 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34849584
5.
Metabolic impact of genetic and chemical ADP/ATP carrier inhibition in renal proximal tubule epithelial cells.
Arch Toxicol
; 97(7): 1927-1941, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37154957
6.
Brothers in Arms: ABCA1- and ABCG1-Mediated Cholesterol Efflux as Promising Targets in Cardiovascular Disease Treatment.
Pharmacol Rev
; 72(1): 152-190, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31831519
7.
Safety of drug use in patients with a primary mitochondrial disease: An international Delphi-based consensus.
J Inherit Metab Dis
; 43(4): 800-818, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32030781
8.
Organic anion transporters 1 and 3 influence cellular energy metabolism in renal proximal tubule cells.
Biol Chem
; 400(10): 1347-1358, 2019 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30653465
9.
Comment on "A severe linezolid-induced rhabdomyolysis and lactic acidosis in Leigh syndrome".
J Inherit Metab Dis
; 44(1): 6-7, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33159463
10.
Mitoenergetic Dysfunction Triggers a Rapid Compensatory Increase in Steady-State Glucose Flux.
Biophys J
; 109(7): 1372-86, 2015 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26445438
11.
Statin Lactonization by Uridine 5'-Diphospho-glucuronosyltransferases (UGTs).
Mol Pharm
; 12(11): 4048-55, 2015 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26412035
12.
Unlocking mitochondrial drug targets: The importance of mitochondrial transport proteins.
Acta Physiol (Oxf)
; 240(6): e14150, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38666512
13.
Pyruvate dehydrogenase is a potential mitochondrial off-target for gentamicin based on in silico predictions and in vitro inhibition studies.
Toxicol In Vitro
; 95: 105740, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38036072
14.
Statins and Cardiomyocyte Metabolism, Friend or Foe?
J Cardiovasc Dev Dis
; 10(10)2023 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37887864
15.
Mitochondrial complex III activity: from invasive muscle biopsies to patient-friendly buccal swab analysis.
Sci Rep
; 13(1): 9638, 2023 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37316639
16.
Prolonged Moderate-Intensity Exercise Does Not Increase Muscle Injury Markers in Symptomatic or Asymptomatic Statin Users.
J Am Coll Cardiol
; 81(14): 1353-1364, 2023 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37019582
17.
Dissecting Drug-Induced Cytotoxicity and Metabolic Dysfunction in Conditionally Immortalized Human Proximal Tubule Cells.
Front Toxicol
; 4: 842396, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35295229
18.
Restoring cellular NAD(P)H levels by PPARα and LXRα stimulation to improve mitochondrial complex I deficiency.
Life Sci
; 300: 120571, 2022 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35469913
19.
Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer.
Mol Metab
; 60: 101469, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35278701
20.
Development and validation of a high-content screening in vitro micronucleus assay in CHO-k1 and HepG2 cells.
Mutat Res
; 724(1-2): 7-21, 2011 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21658468